Republicans didn’t seem to have a problem when politicians like Sen. Rand Paul, Rep. Thomas Massie, and Rep. Andy Harris tried to insert themselves into local D.C. politics this year, but then again, they’re all Republicans. Now some GOP operatives are going hard at Democratic Sen. Mary Landrieu of Louisiana for trying to speak on behalf of D.C. residents, who don’t have representation in the Senate.

American Crossroads—-the Karl Rove-founded Super PAC—-released a biting one-minute ad today painting Landrieu, who is facing a tough reelection bid against Republican Bill Cassidy, as a senator representing D.C., not Louisiana. The ad pastes together a bunch of news clips in which people are commending all the work Landrieu has done on behalf of D.C. residents.

“The District of Columbia, which has about 650,000 people, I want to speak on their behalf,” Landrieu says.

At one point, there’s a clip of Mayor Vince Gray calling Landrieu the “senator representing the District of Columbia until we become the 51st state.”

Landrieu has recently come under fire for not actually owning a home in Louisiana—-she has used her parents’ address—-yet having a $2.5 million home in Capitol Hill. A state legislator even sued her, contending that she lives in Washington and is ineligible to represent Louisiana.

So does this ad mean that American Crossroads believes that D.C. should be autonomous, or, at the very least, that national politicians shouldn’t interfere with local affairs? We’d guess probably not. After all, Massie, who is also up for re-election, says he introduced legislation to gut D.C.’s gun laws to show his Kentucky constituents that he is pro-guns—-and American Crossroads has yet to run an ad about that.